Research On: Chloramphenicol Loaded Nanofibre With Pmma & PVPK90 For Ocular Disc Or Insert For Eye Infection
Year: 2024
Type: article
Abstract: The electrospun chloramphenicol loaded nanofibre with PMMA and PVPK90 fibers were prepared effectively. The fiber with a smooth surface that contained 0.2 grams of chloramphenicol showed an increased medication content for the purpose of treating eye related problems. Strong antioxidant, antibiotic, antifungal, in eye infection, chloramphenicol is also useful for various ailments. In comparison to the equivalent films, the thermal, mechanical, and drug release characteristics of the chloramphenicol fibers were examined. With this understanding, efforts were made to optimize the manufacturing of electrospun SDPF with chloramphenicol, a more effective antibiotic medication. In this work, we report the creation of an efficient nanofibre (NF) formulation that releases the best antibiotic medication, chloramphenicol, for use in eye infection. It does this by embedding the polymers PMMA and PVPK90, which are inexpensive and widely available.
Author: Omprakash G. Bhusnure , Shivam S. Vyavahare , Mani Ganesh , D. D. Vibhute , Vijayendra swammy, Hyun Tae Jang
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6930702337
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