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The association of angular cheilitis and HIV patients

Year: 2024

Type: article

Abstract: Angular cheilitis (AC), an inflammatory condition affecting the corners of the mouth, is commonly observed in HIV-positive populations and has potential as a clinical marker of immune suppression. This scoping review systematically examined studies to assess the association between AC HIV-positive individuals, with a particular focus on CD4+ cell counts and viral loads. A literature search across PubMed, ScienceDirect, and Google Scholar identified relevant studies, emphasizing the clinical characteristics, prevalence, and immunological indicators associated with AC. Findings indicate that AC prevalence increases as CD4+ counts decline, suggesting its utility as an early marker of HIV progression. The data also reveal a high co-occurrence of AC with oral candidiasis, further supporting its association with advanced immunosuppression. Statistical analyses from reviewed studies demonstrated significant correlations between low CD4+ levels and increased risk of AC, reinforcing the potential of AC as a diagnostic cue for immune decline. This review highlights AC as a non-invasive and cost-effective marker that could support early diagnosis and intervention in resource-limited settings, thereby improving HIV management outcomes.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.15182837

Authors: Reiska Kumala Bakti, Yasmin Kamila Putri, Indah Alya Zahra, Dhea Rima Rohita Zulfa

Institution: Universitas Airlangga

Language: English

Topic: HIV/AIDS oral health manifestations

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6930822837

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