Pharmaceutico-Analytical Evaluation Of Khadira Lauha: A Classical Iron-Based Formulation In The Management Of Pandu Roga
Year: 2024
Type: article
Abstract: Background: Khadira Lauha is a classical Ayurvedic herbo-mineral formulation containing Lauha Bhasma (iron calx), Khadira (Acacia catechu), and other ingredients, traditionally indicated in Pandu Roga (anemia). With the rising demand for standardized and evidence-based traditional medicines, it is crucial to evaluate this formulation through pharmaceutico-analytical methods to ensure its safety, purity, and efficacy. Objectives: To prepare Khadira Lauha following classical guidelines and to carry out its detailed pharmaceutico-analytical evaluation for assessing its standardization parameters and therapeutic potential in the context of Pandu Roga. Materials and Methods: Khadira Lauha was prepared using the classical Ayurvedic method, incorporating Khadira Sara, Triphala, Trikatu, Lauha Churna, and Gomutra The formulation underwent standard organoleptic, physicochemical, and instrumental analyses such as pH, LOD (Loss on Drying), total ash, acid insoluble ash, HPTLC fingerprinting, XRD, and SEM studies. Results: The formulation showed acceptable organoleptic characteristics, with a metallic taste and dark brown appearance. Physicochemical parameters such as pH (5.2), LOD (2.65%), total ash (10.1%), and acid insoluble ash (2.8%) were within permissible limits. HPTLC confirmed the presence of phytoconstituents from Khadira, while SEM revealed uniform particle size below 10 microns. XRD analysis validated the crystalline nature of iron compounds, indicating the presence of Lauha Bhasma in a stable form. Discussion: The study confirms that Khadira Lauha prepared through traditional methods adheres to modern pharmaceutical quality parameters. The integration of classical and contemporary analytical techniques helps to establish the therapeutic reliability of the formulation in Pandu Roga by supporting iron supplementation through biocompatible and safe Ayurvedic compounds. Conclusion: The pharmaceutico-analytical standardization of Khadira Lauha ensures its identity, purity, and quality. The formulation, validated through modern tools, stands as a promising classical alternative for the management of iron-deficiency anemia (Pandu Roga), advocating its further clinical evaluation and large-scale standard production.
Authors: Dr. Anand Chandra Mishra, Dr. Anshumaan Mishra
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6930995045
FWCI:
Cites:
Cited by:
Related to: