General Pathophysiological Mechanisms of Inflammation
Year: 2025
Type: article
Abstract: This scientific paper explores the general pathophysiological mechanisms of inflammation, a fundamental biological response to harmful stimuli such as infection, injury, or immune dysregulation. The study provides a comprehensive overview of the key stages of inflammation, including initiation, amplification, and resolution, as well as the complex cellular and molecular components involved. Special emphasis is placed on immune cells such as macrophages, neutrophils, and lymphocytes, along with inflammatory mediators including cytokines, chemokines, prostaglandins, and nitric oxide. The work distinguishes between acute and chronic inflammation, explaining their unique features, triggers, and pathological consequences. Disruption in this process is highlighted as a major contributor to long-term inflammatory conditions such as autoimmune disorders, cardiovascular disease, and cancer. Clinical implications, diagnostic markers, and therapeutic strategies targeting specific pathways of inflammation are also addressed. This research is intended to serve as a valuable resource for students of medical and biological sciences, healthcare professionals, and researchers interested in immunology and disease mechanisms.
Authors: Sultanov Samadjon, Yusupova Shaxlo, Aliyeva Bibixon
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6931079708
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