Supplementary files: Chromosome-level genome assembly and single-cell analysis unveil molecular mechanisms of arm regeneration in the ophiuroid Ophiura sarsii vadicola
Year: 2025
Type: supplementary-materials
Abstract: This study establishes a chromosome-level genome assembly of Ophiura sarsii vadicola and elucidates arm regeneration’s cellular and molecular dynamics in ophiuroids through combined with bulk and single-cell transcriptomic profiling. The supplementary files supporting this study are listed herein: Additional files for the main text: (1) 1_Additional file 1_Figures.docx for 12 supplementary figures (Additional File 1: Fig. S1-S12) and (2) 2_Additional file 2_Tables.docx for 22 supplementary tables (Additional File 2: Table S1-22). Script for cross-species analysis: 3_across_analysis.r Bulk-RNA sequencing results: 4_Bulk_RNAseq_expression matrix.no.norm, expression dataset without normalization. Original photo for immunohistology observation: 5_Histology_observation_Fig2.zip, including two original photos (jpg), the original view file (S081301 masson.mrxs and the folder of S081301 masson), the software to view original file (CaseViewer: downloading source:https://www.3dhistech.com/solutions/caseviewer/) scRNA cell cluster data: (1) 6_scRNA_seurat_allCellcluster.Rda.zip includes one dataset file for cell clusters of CT I and CT Ⅱ cells, Muscle, Nerve, Immune, and Endothelial cells (2) 6_scRNA_seurat_CT_cells_data.zip includes the detailed clustering datasets for CT I (CT I.rda) and CT Ⅱ cells (CT Ⅱ.rda), separately.
Source: Figshare
Authors: Yixuan Li (14760574), Wenge Shi (11851046), Qinzeng Xu (15210714)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6940019567
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