Year: 2024
Type: article
Abstract: \nThe level of expression of \nsrfAD gene, a subunit AD of surfactin synthetase, and the yield of the total lipopeptide fraction were studied in relation to the composition of nutrient medium and the growth stage of the probiotic strain Bacillus subtilis GM5. The maximum concentration of the total lipopeptide fraction was observed during the growth of strain GM5 on SMN medium with soybean flour. The relative expression of the srfAD gene of B. subtilis GM5 was quantified by RT- qPCR. We conclude that the increase in the concentration of the total lipopeptide fraction on SMN medium correlates with the expression of the srfAD gene during 96-hour cultivation of GM5, which may indicate the production of mainly lipopeptide from the surfactin group by under these conditions.\n
Authors: Guzel Lutfullina, Adela Abubakirova, Marat Lutfullin, Ayslu Mardanova
Institution: Kazan Federal University
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Russian Science Foundation
Award: G7991863580
OpenAlex ID: W6940593281
FWCI:
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