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Phytochemical profiling and evaluation of antimicrobial properties of Papilionanthe teres leaves extracts and their green synthesized silver nanoparticles

Year: 2025

Type: article

Abstract: The study was performed to investigate the phytochemical profile and antimicrobial activity of Papilionanthe teres leaves (PTL) and their synthesized silver nanoparticles (AgNPs-PTL). Preliminary phytochemical profiling confirmed the presence of flavonoids, phenols, triterpenoids, steroids, and carbohydrates that can exert various pharmacological activities. Further, comprehensive GC-MS and HPTLC analyses identified the presence of 56 and 4 bioactive compounds, respectively. Characterization techniques like UV-Vis spectroscopy, FTIR, XRD, SEM, DLS, and EDX verified the crystalline structure, spherical shape, and nanosize of AgNPs-PTL. Silver nanoparticles synthesized using P. teres leaves extract (AgNPs-PTL) exhibited strong antimicrobial activity compared to the plant extract alone. AgNPs-PTL exhibited higher antimicrobial activity against E. coli than S. aureus, highlighting their biomedical relevance. So, this research highlights the significant antimicrobial potential of P. teres leaves and their green-synthesized silver nanoparticles, emphasizing their eco-friendly, cost-effective, and green synthesis. These findings support the development of novel medications to improve human health, validating the medicinal value of the P. teres plant and its AgNPs-PTL in treating microbial infections and their associated diseases and promoting sustainable drug development. • Phytochemical profiling of Papilionanthe teres leaves using GC-MS and HPTLC. • Green synthesis of AgNPs from the leaves of Papilionanthe teres . • The green synthesized AgNPs were characterized by UV, FTIR, DLS, XRD, EDX, and SEM. • Green-synthesized AgNPs showed potent antimicrobial properties.

Source: The Microbe

DOI: 10.1016/j.microb.2025.100475