Year: 2026
Type: article
Abstract: Coffee beans as beverages that contains acrylamide that formed in roasted process. Acrylamide can make multiple organ dysfunction on rats. The atudy aims to prove the effect of Robusta on Morphological changes of Hepatocytes, colonic mucosa, and prostatic acinar on Male rats . True experimental post test only control group design. 24 samples of male rats clustered in 5 groups; control group and treatment group were given steeping doses of coffee (0.36ml, 0.72ml, 1.44ml, and 2.16ml). Analysis of the data using One-Way ANOVA showed that there are significant value 0.000. Steeping of robusta coffee (Coffea canephora var. Robusta) could cause morphological changes of hepatocytes cell, colonic mucosa, and prostatic acinar in male rats (Rattus novergicus Strain Wistar).
Authors: Dian Y. Lestari, M. Aleq Sander, Halida Nelasari, Anung P. Ilahika, Saidah Rahmat, Meta Sophia, Deby Rahman
Institution: Universitas Muhammadiyah Malang
Language: English
Topic: Coffee research and impacts
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W6942225507
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