Year: 2022
Type: article
Abstract: Magnetic particle imaging (MPI) is an emerging non-invasive molecular imaging method that can image the concentration and position of superparamagnetic iron oxide (SPIO) nanoparticles. However, the scalability of magnetic particle imaging (MPI) is the major barrier to its clinical use now. For a human bore size of MPI, it is important to achieve a high magnetic gradient for high image resolution with a large enough field-of-view (FOV) for most of body part. In this paper, we present a human-scale amplitude modulation (AM) MPI system with a bore size (200 mm) and using a superconductor that generated a high MPI magnetic gradient of up to 2.5 T/m/µ0 and a 1D-FOV of 100 mm (with a feasible 3D FOV of 140 × 140 × 100 mm). The results of this paper show that the promise of MPI for human application is not far away.
Authors: Le, Tuan-Anh, Bui, Minh Phu, Gadelmowla, Khaled Mohamed, Oh, Seungjun, Yoon, Jungwon
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W6944240704