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Stimulation of the reparative activities in human chondral defects via alginate hydrogel-guided rAAV sox9 and TGF- β gene delivery

Year: 2024

Type: conference-paper

Abstract: Objectives: Recombinant adeno-associated virus gene vectors (rAAV) are promising vehicles to treat focal cartilage defects when delivered via biomaterials [ref:1]. The objective was to test whether rAAV carrying the reparative sox9 and TGF-β genes in an alginate hydrogel can stimulate [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dkou536

Authors: Liu, Wei, Venkatesan, Jagadeesh K., Wang, Dan, Schmitt, Gertrud, Sahin, Ebrar, Dahhan, Ola, Madry, Henning, Cucchiarini Madry, Magali

Institutions: Universitätsklinikum des Saarlandes, Saarland University

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6946003659

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