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Thermonuclease NucA makes Staphylococcus aureus highly pathogenic for septic arthritis

Year: 2024

Type: conference-paper

Abstract: Objectives: Gram-positive Staphylococcus aureus are the most common cause for septic arthritis in humans. The mature thermonuclease Nuc1 (known as NucA) is secreted by S. aureus and plays an important role in its virulence. NucA degrades extracellular DNA and RNA, and thus contributes to bacterial escape [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dkou516

Authors: Li, Ningna, Deshmukh, Meghshree, Sahin, Filiz, Hafza, Nourhane, Ammanath, Aparna, Weber, Alexander, Jin, Tao, Ehnert, Sabrina, Götz, Friedrich

Institutions: University of Tübingen, University of Gothenburg, BG Klinik Tübingen, Goethe University Frankfurt

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6946328138

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