Work

CA074Me attenuates titanium nanoparticle-induced osteolysis via inhibition of macrophage NLRP3 inflammasome activation and osteoclast differentiation

Year: 2024

Type: conference-paper

Abstract: Objectives: Aseptic loosening due to peri-implant osteolysis remains the leading cause of long-term implant failure. Increasing evidence suggests that wear debris-induced NLRP3 inflammasome activation in macrophages and subsequent inflammatory osteoclast activation play an essential role in the progression [for full text, please go to the a.m. URL]

Source: German Medical Science (German Research Foundation)

DOI: 10.3205/24dkou156

Authors: Schildberg, Frank A., Zhang, Li, Zhu, Mengbo, Haddouti, El-Mustapha, Schmidt, Florian I., Burger, Christof, Wirtz, Dieter C.

Institutions: University of Bonn, University Hospital Bonn

Language: English

Topic: Orthopaedic implants and arthroplasty

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6946484054

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