Year: 2025
Type: preprint
Abstract: This work presents a framework for modeling three-dimensional scaffold-mediated bone regeneration and the associated optimization problem. By incorporating microstructure into the model through periodic homogenization, we capture the effects of microscale fluctuations on the bone growth process. Numerical results and optimized scaffold designs that explicitly account for the microstructure are presented, demonstrating the potential of this approach for improving scaffold performance.
Source: arXiv (Cornell University)
Authors: Dondl, Patrick, Suchan, Oliver
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6948111145
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