Formulation and Evaluation of Paracetamol Mouth Dissolving Films
Year: 2024
Type: article
Abstract: as mouth dissolving films (MDF), are novel dosage forms designed to disintegrate or dissolve within the oral cavity, offering a convenient way to administer medications. A mouth dissolving film of Paracetamol was successfully developed, with the concentration of polymer and plasticizer significantly affecting the formulation. The solvent casting technique demonstrated excellent film-forming properties and mechanical strength. Among the formulations, F6 showed the fastest disintegration time of 45 seconds and released 98.78% of the drug within 8 minutes. Stability studies further confirmed the film's robustness, making it a promising option for pediatric pain and fever treatment.
Author: Jadhav S.B., Lonikar N.B., . Muli P.N., Sonvane S.M., Mahajan P.S.
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6949082273
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