A Review on Analytical Applications Of 1,10-Phenanthroline as Chromogenic Reagent
Year: 2025
Type: article
Abstract: Chromogenic reagents play a pivotal role in pharmaceutical analysis by facilitating the detection and quantification of key analytes through precise colorimetric reactions. Among these, 1,10-phenanthroline is a versatile and highly sensitive reagent that forms stable metal complexes, making it indispensable in spectrophotometric, electrochemical, and chromatographic techniques. This article explores the diverse applications of 1,10-Phenanthroline in the quantitative determination of pharmaceuticals and metal ions, emphasizing its role in quality control, environmental monitoring, and advanced analytical methodologies. Spectrophotometric methods leveraging 1,10-Phenanthroline offer rapid, cost-effective, and highly accurate alternatives for drug and metal ion analysis, demonstrating excellent sensitivity and reproducibility. Additionally, emerging techniques such as flow-injection photometry, FTIR spectroscopy, and electrochemical sensors further expand its utility in modern analytical chemistry. The review underscores the growing significance of 1,10-Phenanthroline -based methodologies in ensuring pharmaceutical safety, regulatory compliance, and enhanced analytical precision.
Author: Patlolla Nikitha Reddy, Pagadipally Santhosh Kumar, Bugga Veena, Anumolu Durga Pani Kumar, Naraparaju Swathi*
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6949084867
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