Evaluation of antimicrobial, antioxidant, antidiabetic activities, and acute toxicity of Elephantopus scaber L.
Year: 2025
Type: article
Abstract: Elephantopus scaber L., a medicinal plant from Myanmar, was studied to evaluate its biological activity. The activity of antimicrobial assessment showed that ethyl acetate extract exhibited moderate activity in contrast to all six tested organisms. Using the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assay with ascorbic acid as standard for antioxidant activity showed that ethyl acetate extract possessed 36.28 μg/mL. The in vivo antidiabetic activity with glipizide, as a standard hypoglycemic agent was employed to determine antidiabetic activity. The data parameter under observation for Elephantopus scaber L. reaches its peak at 135 minutes, with a 39.0% reduction. No toxic behavior was observed at the limited tested concentrations (2000 mg/kg and 5000 mg/kg) and it suggested a favorable safety profile.
Author: Mediterranean Journal of Pharmacy and Pharmaceutical Sciences
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6949286421
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