Comprehensive Review on Analytical Method Development and Validation: Focus on HPLC Techniques
Year: 2025
Type: article
Abstract: High Performance thin-layer liquid chromatography refers to a feasible, sophisticated analytical method established upon thin-layer chromatography (TLC) concepts that offers several important advantages, including better material application, quicker and more efficient separation and lower mobile phase usage. The intent of this investigation had been to provide a quick as well as easy HPTLC approach to Piroxicam identification. The suggested technique can be applied to detect the substances under analysis at extremely low quantities. The suggested approach is straightforward, eco-friendly, stable, sensitive, and economical. It could be applied to regular quality control procedures or research. The primary purpose for HPLC validation is essential to ensure the process stays within predetermined bounds under expected circumstances. Examine deviations from predetermined parameters, take corrective action, think about if revalidation was required, and make adjustments to the process or product. Then, assess the impact of the changes by evaluating the equipment, personnel, environment, process, and product.
Author: D. Kawade*1, Aishwarya Shrirao2, Irshad Ahmad Mohd Salim3
Language: English
Subfield: Analytical Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6949287735
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