Comparison of Antioxidant Vitamins and Enzymes in Patients with Alcoholic Liver Disease in North Karnataka Population
Year: 2024
Type: article
Abstract: Background: Liver is the major site for metabolism. Ingestion of alcohol produces striking metabolic imbal-ances in the liver, causing the formation of Reactive Oxygen Species (ROS). Inadequate removal of ROS may cause cell damage, attacking lipo-proteins and inactivating enzymes. Method: 95 Alcoholic liver disease patients were compared with the same number of healthy (control) groups. Clinical and laboratory investigations were carried out using venous blood plasma vitamin E levels by the Baker-Hatal method, ascorbic acid by the Teitz method, and SVD by the Beers-Seizer method. Results: The comparison of non-enzymatic oxidant parameters. Ascorbic acid, vitamin E, and the comparison of antioxidant enzymes SOD and GPX in both groups were statistically highly significant (p<0.00). Conclusion: It is proved that increased anti-oxidant enzymes except catalase and decreased non-enzymatic oxi-dants have diagnostic value in alcoholic liver disease patients.
Authors: Ambrish Avate, Uday Kumar Patil
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6949302518
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