Review On Nanorobots in Cancer Treatment
Year: 2025
Type: article
Abstract: Nanorobots represent a groundbreaking advancement in cancer treatment, offering precise and targeted therapeutic approaches at the molecular level. These nanoscale devices are engineered to navigate through the bloodstream, identify malignant cells, and deliver therapeutic agents with high specificity, minimizing damage to healthy tissues. Nanorobots can be designed with functionalities such as active drug release, real-time imaging, and tumor-specific targeting, enhancing treatment efficacy while reducing systemic toxicity. The integration of biosensors, molecular recognition elements, and stimuli-responsive mechanisms enables nanorobots to detect tumor microenvironments and initiate site-specific therapeutic actions. Functionalized with ligands or antibodies, they improve tumor cell recognition and penetration. Additionally, nanorobots can be powered by external magnetic fields, chemical reactions, or self-propulsion mechanisms, enhancing their ability to reach deep-seated tumors. Recent advancements have demonstrated promising results in preclinical models, showcasing their potential for precise drug delivery, photothermal therapy, and gene editing strategies in oncology. However, challenges such as immune system evasion, large-scale fabrication, biocompatibility, and regulatory approvals must be addressed before clinical translation. Nanorobotic technology holds immense promise for revolutionizing cancer therapy by improving treatment precision, reducing side effects, and enhancing patient outcomes. Future research must focus on optimizing their design, safety, and functionality to accelerate clinical applications and integrate them into mainstream oncology treatments. With continued advancements, nanorobots could redefine the landscape of personalized cancer therapy, offering a novel paradigm in the fight against cancer.
Author: Suma Sri Potti*, Mane Kota Vinay Kumar, Noudu Bhavya Sri, Bhimadolu Aishwarya, Padala Ramya Dhanasri, Gumparthi Mani Naga Durga Mallika, Guggilapu Rakesh
Language: English
Topic: Micro and Nano Robotics
Subfield: Condensed Matter Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6949433457
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