Pharmacogenomics In Personalized Medicine
Year: 2025
Type: article
Abstract: Pharmacogenomics, the study of how an individual's genetic makeup influences their response to drugs, has emerged as a pivotal component in the realm of personalized medicine. The paper begins by elucidating the fundamental principles underlying pharmacogenomics and its role in optimizing drug therapy. It examines the link between genetic variations, drug metabolism pathways, and treatment outcomes, emphasizing the importance of identifying genetic biomarkers to predict drug response and adverse reactions. Recent breakthroughs in pharmacogenomic research have revolutionized clinical practice, enabling clinicians to make more informed decisions regarding drug selection, dosing, and monitoring. Discoveries of new genetic variants associated with drug metabolism to the development of sophisticated pharmacogenetic testing platforms, these advancements have paved the way for personalized approaches to patient care. One of the key findings underscored in this paper is the significant impact of pharmacogenomics on enhancing medication efficacy and safety across various therapeutic areas. By tailoring treatment regimens based on individual genetic profiles, healthcare providers can minimize the risk of adverse drug reactions and improve patient outcomes. Moreover, pharmacogenomic-guided dosing strategies also optimize therapeutic effectiveness while treatment failure or toxicity. Furthermore, the paper enhances pharmacogenomic testing in clinical settings and its integration into electronic health records, enhancing personalized healthcare delivery. Pharmacogenomics can significantly enhance medication management in complex conditions like cancer, cardiovascular diseases, and psychiatric disorders. In conclusion, this review underscores the transformative impact of pharmacogenomics on personalized medicine, emphasizing recent advances and key findings that underscore its significance in optimizing drug therapy and improving patient outcomes.
Author: Nittal Vekaria*, Pinakinbharthi Goswami
Language: English
Subfield: Pharmacology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6949454304
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