The Drug Physiotens, the Features of the Drug and Its Use in the Field of Cardiology, in Patients With Heavy Body Weight
Year: 2025
Type: article
Abstract: Moxonidine (Fisiotens®) is an antihypertensive drug that selectively interacts with imidazoline I1-receptors located in the brainstem, resulting in a decrease in sympathetic activity and blood pressure (BP). Moxonidine (Fisiotens®) has high affinity to imidazoline I1 -receptors and only slightly binds to central α2 -adrenoreceptors, due to interaction with which dry mouth and sedative effect are mediated; reduces tissue resistance to insulin. Decrease in systolic and diastolic BP at a single and prolonged administration of the drug is associated with a decrease in the pressor action of the sympathetic nervous system on peripheral vessels, reduction of total peripheral resistance (TPR).
Author: Axmedov Shamshod Jamshidovich
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6949570048
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