Incidence of Type 2 Respiratory Failure in Hypothyroidism
Year: 2024
Type: article
Abstract: The study investigates the incidence of Type 2 Respiratory Failure (T2RF) in hypothyroidism among 200 patients, exploring various parameters including age, gender, symptoms, exposure history, and comorbidities. T2RF, characterised by inadequate oxygenation of blood and retention of carbon dioxide, is a critical respiratory condition often associated with underlying medical disorders. Hypothyroidism, a common endocrine disorder resulting from decreased thyroid hormone production, can predispose individuals to respiratory complications, including T2RF, due to metabolic and respiratory muscle dysfunction. Results reveal a 41% incidence of T2RF among participants, indicating a significant burden of respiratory compromise in hypothyroid patients. Symptom analysis indicates prevalent manifestations such as cough with sputum, shortness of breath, and hot flashes, reflecting the clinical complexity of hypothyroidism. Age-wise distribution underscores an increasing trend of T2RF with advancing age, emphasising the need for tailored interventions for older populations prone to respiratory complications. Gender analysis suggests a higher incidence of T2RF among females compared to males within the sampled population, highlighting potential gender-specific risk factors or physiological differences contributing to respiratory dysfunction. Environmental and medical exposures, such as radiation and medication, are identified as potential risk factors, necessitating further exploration of their impact on respiratory health in hypothyroid patients. Comorbidity analysis reveals overlapping health conditions among patients with T2RF, including diabetes mellitus, hypertension, chronic obstructive pulmonary disease, coronary artery disease, and chronic kidney disease. Additionally, smaller cohorts exhibit pneumonia, obstructive sleep apnea, bronchial asthma, and unspecified comorbidities, with varying associations to T2RF. These findings underscore the complex interplay of age, gender, environmental exposures, and comorbidities in the development of T2RF in hypothyroidism, highlighting the importance of comprehensive patient assessment and targeted interventions in clinical management.
Author: Sayad Maseera Fathima, Arshad Shaik
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6949716015
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