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Additional file 16 of Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis

Year: 2025

Type: article

Abstract: Supplementary Material 16 Fig. S12: Validation of siRNA-mediated knockdown in FB2 fibroblasts using quantitative real-time PCR analysis of GAPDH, HGF, NRG1α, and NRG1β mRNA levels. FB2 fibroblasts were transfected with siRNAs targeting HGF (siHGF_1–3), NRG1 (siNRG1_1–3), a scrambled control siRNA, or a GAPDH-targeting siRNA as positive control (n = 2). Data are presented as mean ± SD.

Source: Figshare

Authors: Daum, Ann-Kathrin, Schlicker, Lisa, Schneider, Marc A., Muley, Thomas, Klingmüller, Ursula, Schulze, Almut, Thomas, Michael, Christopoulos, Petros, Sültmann, Holger

Institutions: German Cancer Research Center, Heidelberg University, German Center for Lung Research, University Hospital Heidelberg

Language: English

Topic: Lung Cancer Treatments and Mutations

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6958791953

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