Vitamin B3 deficiency: the right clinical information, right where it's needed
Year: 2025
Type: article
Abstract: Vitamin B3, also referred to as niacin, is the generic term for nicotinic acid, its amide (nicotinamide or niacinamide), and their biologically active derivatives. It is also found in the form of the pyridine nucleotide coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADPH). These are essential in all cells for energy production, metabolism, and DNA repair. Severe deficiency results in pellagra, which is a combined deficiency of both niacin and its precursor, tryptophan. The symptoms of deficiency are primarily dermatitis, diarrhoea, and dementia. Death results if the condition is untreated.
Source: Figshare
DOI: 10.14749/29348543
Author: Human Sciences Research Council
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: Human Sciences Research Council
OpenAlex ID: W6960978616
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