Effect of Protein Concentration on the Corrosion Behavior of Magnesium Alloys
Year: 2025
Type: article
Abstract: When magnesium alloy is used in the human physiological environment， it will be affected by protein.In this work， the corrosion mechanism of a magnesium alloy in phosphate-buffered saline (PBS) containing various concentrations of bovine serum albumin (BSA) (0，0.5， 1.0， 1.5， 2.0， 3.5 and 5.0 g/L) was systematically investigated.Surface characterisation was carried out by Fourier-transform infrared spectroscopy (FTIR)， scanning electron microscopy (SEM)，energy-dispersive spectroscopy (EDS) and contact-angle measurements，whereas electrochemical behaviour was evaluated through potentiodynamic polarisation， electrochemical impedance spectroscopy (EIS) and scanning electrochemical microscopy (SECM).Complementary immersion tests were performed to corroborate the electrochemical findings.To elucidate the time-dependent effect of protein concentration， the electrochemical response and corrosion products of specimens immersed for 1， 3 and 7 d in solutions containing 0， 2.0 and 5.0 g/L BSA were also examined.Results showed that the presence of BSA up to 2.0 g/L reduced the corrosion rate， and the minimum corrosion current density occurred at 2.0 g/L，whereas a higher concentration (5.0 g/L) of BSA significantly accelerated localized corrosion of magnesium alloy surface.In the later stages of immersion， the overall corrosion resistance of the alloy deteriorated.When the BSA concentration was kept below 2.0 g/L， protein molecules formed a monolayer via chemisorption on the alloy surface， leading to a continuous decrease in corrosion rate with increasing BSA concentration.During prolonged immersion， this non-dense adsorbed layer was penetrated by the corrosive medium and consequently lost its protective effect.At 5.0 g/L BSA， protein molecules chelated the metal ions released from the alloy， forming soluble complexes that accelerated corrosion.With further immersion， the continual deposition， detachment and chelation of high-concentration BSA further intensified the dissolution of the magnesium alloy.
Author: MA Yucong, WANG Pengjie, OUYANG Zhengzheng, Mohd TALHA, LIN Yuanhua
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6962730798
FWCI:
Cites:
Cited by:
Related to: