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Optogenetic modulation of peripheral nociceptive neurons with biocompatible optoelectronic implants

Year: 2024

Type: article

Abstract: This study demonstrates the development and validation of a soft optoelectronic implant for the sciatic nerve, using yellow light to inhibit nociceptive neurons. Optogenetic inhibition significantly reduces nociceptive mechanical and thermal pain sensitivity in mice, offering a promising non-pharmacological approach to treat chronic pain without affecting normal sensory function. Raw data corresponding to the study.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.13757010

Author: Chu Sin Chung, Paul

Institution: Centre Hospitalier Universitaire Vaudois

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6967753485

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