Management Strategies and Treatment Outcomes in Pediatric Portal Hypertension: A Retrospective Study
Year: 2024
Type: article
Abstract: Background: Pediatric portal hypertension is a significant condition associated with considerable morbidity, including variceal bleeding, growth failure, and other complications. Despite advances in medical care, optimal management strategies and treatment outcomes remain an area of ongoing research, especially in pediatric populations. Objective: This study aimed to evaluate the effectiveness of various management strategies and their associated outcomes in children with portal hypertension. Methods: A retrospective observational study was conducted, analyzing data from 100 pediatric patients diagnosed with portal hypertension over a 12 to 18-month period. Patients were categorized based on the treatment modality received: Medical Therapy, endoscopic interventions, or surgical procedures. Data were collected from medical records and analyzed to evaluate symptom resolution, growth improvement, and complications. Results: Endoscopic and surgical interventions were associated with higher rates of symptom resolution (80% and 85%, respectively) and growth improvement (70% and 78%, respectively) compared to medical Therapy. Portal pressure reduction was documented in 82% of the cohort. Complications were minimal, with slightly higher rates in surgical interventions. Statistical analysis confirmed the significant efficacy of invasive modalities over medical Therapy. Conclusion: Endoscopic and surgical interventions demonstrate superior outcomes in managing pediatric portal hypertension. The findings underscore the need for early diagnosis, tailored treatment strategies, and multidisciplinary care. Further research is warranted to validate these results and explore innovative management approaches.
Authors: Mayank Priyadarshi, Sanjay Kumar, Sunil Kishore
Institution: Indira Gandhi Institute of Medical Sciences
Language: English
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6967763871
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