Development of Rectal Suspension for Use in Bowel Treatment
Year: 2024
Type: article
Abstract: Rectal administration is an effective drug for the local and systemic administration of active substances. The rectal environment is relatively stable and its enzyme activity is low, it is favorable for drugs with plow oral absorption, extensive first metabolism, gastric irritation, gastric environment persistent problems, local activity, and drugs that cannot be administered in other ways. This invention relates to the use of xanthan gum and Carbomer, especially in the form of an enema for treating inflammatory bowel disease (IBD), and compositions for rectal administration. Contains Mesalazine as a therapeutically active ingredient.
Authors: Kubra Yilmaz, Cuneyt Toprak, Gokay Gun, Erdınc Babuc
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6967818030
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