Microwave Assisted One-Pot Multicomponent Synthesis of Amino Pyrazoles and its derivatives in Green Media
Year: 2024
Type: article
Abstract: : A straightforward one-pot synthesis involving three components-5-amino-1,3-diphenyl-4,5-dihydro-1H-pyrazole-4-carbonitrile derivatives—was carried out under microwave radiation employing substituted aryl aldehyde, malononitrile, and phenyl hydrazine in catalytic amount of baker’s yeast in water as a high performance at room temperature. The recently created approach has faster reaction times, higher quantitative yields, simpler product isolation, green reaction conditions, and a straightforward workup process. Using TLC, Melting point and spectroscopic techniques such as, IR, 1HNMR, and Mass, the structure of the produced derivatives was verified
Authors: Gaikwad, R. N., Chate, B.N.
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6967892808
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