Immuno-onco-genetics: where are we today?
Year: 2025
Type: article
Abstract: Immuno-oncology has progressed and produced several pivotal insights for the enhancement ofimmunotherapy, including the tumor immune microenvironment (TIME) and systemic immunity. Nonetheless,responses to immunotherapy can differ markedly across studies. The principal factor contributing to thislimitation is intratumoral heterogeneity, which is regulated by genetic factors. There is an increasing interest inassociating immune-related genes with systemic immune activity and TIME in the context of cancer. Theimmunogenetic landscape of cancer cells signifies a new comprehension, and immuno-oncogenetics functionsas an approach to clarifying this field. This article summarizes the updated paradigm and offersrecommendations for the future development of immuno-onco-genetics.Keywords: Immuno-onco-genetics, tumor immune microenvironment
Source: Genetics
Authors: Murtadho, Fadhiil Ansyarullah, Yaqin, Muhammad Ainul
Institution: Hasanuddin University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,477
OpenAlex ID: W6967896342
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