Optimizing Herbal Permeation Enhancers for Enhanced Efficacy in Transdermal Patches
Year: 2024
Type: article
Abstract: Transdermal drug delivery systems (TDDS) represent a feasible choice for the non-invasive, long-term delivery of medication. Herbal permeation enhancers, which capitalise on the innate properties of natural substances to promote drug penetration across the skin barrier, have emerged as significant TDDS adjuncts. By studying the mechanisms behind the activity of herbal permeation enhancers, these abstracts demonstrate how these agents may improve medication bioavailability and therapeutic efficacy. Herbal components that exhibit permeation-enhancing properties include terpenes, flavonoids, and essential oils. These components modulate skin permeability and promote medication solubility. Concerns regarding synthetic enhancers are alleviated by the high safety profiles and biocompatibility of herbal permeation enhancers. Moreover, the synergistic interactions between herbal boosters and pharmaceutical molecules improve effective transdermal dispersion. This talk reviews recent advancements in the use of herbal permeation enhancers in a variety of therapeutic categories, highlighting the significance of these agents in enhancing patient compliance and medication delivery efficiency.
Author: Abhijeet R. Ghule*, Archana K. Gaikwad, Vaibhav M. Hiwale, Kulddep S. Kanade
Language: English
Subfield: Pharmaceutical Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6967907006
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