Work

Transcriptomic Landscape of Meningiomas: Analysing Gene Expression Profiles Across Different Anatomical Locations.

Year: 2025

Type: article

Abstract: Meningiomas are the most common adult brain tumors and are approximately 30% of all intracranial neoplasms (1). Multiple studies show that skull base meningiomas (SBM) are more likely to have benign biology whereas tumors with more aggressive behavior can constitute close to 30% of convexity/parafalcine tumor (2). Significant difference in immune-cell gene expression was seen between SBM and convexity meningiomas by Zador Z et al. which explained the biology of the aggressive nature of Non-skull basemeningiomas (NSBM) (3). The gene expression profiles between different anatomical subtypes i.e Skull Base Meningiomas versus Non-skull base meningiomas, remain largely unexplored.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14791826

Authors: Qureshi, Muhammad Binyameen, Amin, Qazi Kamran, Khan, Muhammad Awais, Khan, Faisal

Institutions: Khyber Medical College, CECOS University

Language: English

Topic: Meningioma and schwannoma management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6968089967

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