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CAR-T Cell Therapy: Present and Future Perspectives – A Comprehensive Review

Year: 2024
Type: article
Abstract: Chimeric antigen receptor T-cell (CAR-T) therapy represents a breakthrough in cancer immunotherapy. By engineering T-cells to specifically target cancer cells, CAR-T therapy has demonstrated significant success in treating hematological malignancies such as acute lymphoblastic leukemia (ALL) and non-Hodgkin’s lymphoma. However, challenges like relapse, toxicity, and limited efficacy in solid tumors highlight the need for advancements in the field. This comprehensive review explores the current applications of CAR-T therapy, its limitations, and future directions aimed at optimizing this revolutionary treatment.
Author: Mohammed Ahmed Aliassa et al.
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: hybrid
OpenAlex ID: W6968306529
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