Is Procalcitonin Biomarker for Determining the Severity of Acute Cholangitis?
Year: 2024
Type: article
Abstract: Background Cholangitis is one of the commonest emergencies encountered by gastroenterologists that may warrant drainage of biliary system. Serum procalcitonin (PCT) is an important biomarker of cholangitis with a potential to guide early therapeutic decision. Materials and Methods Our study was conducted on patients who applied to 8 Clinical Hospital and Santa Paraskeva medical center between January 2021 and December 2024 with a diagnosis of AC Results Within the scope of our study, 426 patients were evaluated. 61% (260) were male and 39% (166) were female. The age of the patients ranged from 24 to 88 years with a median age of 56 years. Choledocholitiasis were the most common predisposing factor and were found in 263 patients (62%). Of these, 202 (47.5%) were grade I, 94 (22%) were grade II and 130 (30.5%) were grade III. Conclusion. As a result of the analysis performed in our study, a strong correlation was found between procalcitonin level and disease severity and it was shown that serum procalcitonin level increased as the disease became more severe.
Authors: Fuss J., Voloboyeva A., Polovyj V.
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6968428883
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