Work

Formulation and Evaluation of Microspheres of Nifedipine

Year: 2024

Type: dissertation

Abstract: The aim of the study was to prepare Nifedipine microspheres using Solvent evaporation method using different polymer ratio. FT-IR studies revealed that there was no chemical interaction between the drug and polymer. The average particle size of the optimized formulation was found to be 166 μm. The in-vitro release behavior from all the Nifedipine microspheres was found to be peppas drug release kinetics and produced a sustained release over a period of 12 hours with better entrapment efficiency. Key words: Nifedipine, Eudragit, Carbopol 934p, HPMC, Solvent evaporation method and microspheres.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.14577857

Author: Mohammad Saif*, Dr. D. Venkata Ramana

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6968438376

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