In-Vitro Screening of Antiulcer Potencial of Spathodea Campanulata P. BEAUV
Year: 2025
Type: article
Abstract: Spathodea campanulata, commonly known as the African Tulip Tree, has demonstrated a variety of therapeutic properties in traditional medicine, including potential antiulcer effects.This study explores the use of Spathodea campanulata in the formulation of an antiulcer gel, evaluating its efficacy and safety in treating gastric ulcers. The plant's bioactive compounds, particularly flavonoids, alkaloids, and phenolic compounds, are believed to contribute to its anti-inflammatory, antioxidant, and healing properties, which may help in reducing ulcer formation and promoting mucosal repair. In vitro experiments were conducted to assess Spathodea Campanulata’s ability to prevent ulcer development .Peptic disorders, such as gastro intestinal reflux, gastritis, and peptic ulcers, are common due to stress and improper diet. Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat these disorders, butthey can cause severe side effects. A study evaluated the anti-ulcer activity of the ethanolic extract of Spathodea campanulata leaves by doing in vitro tests. The extract showed anti-ulcer activity against aspirin-induced gastric ulcers, with preliminary phytochemical screening revealing carbohydrates, glycosides, alkaloids, flavonoids, phenols, tannins, and saponin. The study validates the extract's anti- ulcer use in Indian folk medicine, but further research is needed to isolate specific phytochemicals and understand their mechanisms of action.
Author: Gite Jayashri*, Bidave Sakshi, Dr. Datkhile S.
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6968823865
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