Synergistic Cr:Au core shell Nanoparticles combination with Paclitaxel (Taxans)chemo drug on MDA breast cancer cells
Year: 2025
Type: article
Abstract: Dilute wild thyme extraction was synthesized onto Chrome as a core and the core-shell formed when coated with gold by using the green-plasma jet technique. Nanoparticles created in various ratios (1:9, 2:8, 3:7). Consistent results were obtained during the examination of nanoparticles by UV examination, XRD , SEM and TEM, In addition to measuring the rate of cytotoxicity for Chrome@gold core-shell Nps and Chrme@gold core-shell Nps combined with 25 µg, 50 µg, 100µg of taxans chemo therapy on breast cancer cell line (MDA) and in the normal cells line (REF) and The best results was after 72 hours, Where is the maximum rate of toxicity was in 100% concentration of NPs and the least toxicity was in 25% of NPs.
Source: OICC Press Journals
Authors: F. Al-Salmani, Ola, H. Adil, Ban, A. R. Al-Wasiti, Estabraq
Institutions: Ministry of Health, University of Baghdad, Nahrain University
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6973878758
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