Work

Synthesis and Antimicrobial Evaluation of Symmetrical Diquaternary Ammonium Salts Bearing Bis-1,3,4-Oxadiazole Rings Moieties

Year: 2016

Type: article

Abstract: This study describes the synthesis of some novel compounds containing bis-1,3,4-oxadiazole bearing quaternary ammonium salt moieties.The target compounds were prepared from 2-(dimethylamino)ethyl methacrylate (DMAEMA) or 2-(diethylamino) ethyl methacrylate (DEAEMA), using adipic acid as starting material.All the newly synthesized compounds showed satisfactory analytic data for the proposed structures, which were confi rmed by IR and NMR ( 1 H and 13 C) spectroscopy.The newly synthesized compounds were evaluated for their antibacterial activity against various gram-positive and gram-negative strains of bacteria, and the antifungal activities were tested against three phytopathogenic fungi namely, Fusarium oxysporum, Fusarium commune and Fusarium rodelens.Some of the tested compounds displayed promising antibacterial and antifungal activities.

Source: Chemistry Journal of Moldova

DOI: 10.19261/cjm.2016.11(1).07

Authors: Sofiane Daoudi, Tahar Benaissa, Djallal Eddine Adli, Nisserine Hamini-Kadar

Institutions: Université de Saida Dr Moulay Tahar, Université Oran 1 Ahmed Ben Bella

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W2598693727

FWCI:

Cites: 37

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Related to: 10