Work

Age-related changes in osteoarthritic chondrocytes

Year: 2009

Type: dissertation

Abstract: Age is the most important risk factor in the development of osteoarthritis (OA). Numerous studies have now demonstrated that age-related changes occur in both the extracellular matrix and chondrocytes of OA cartilage and such changes are proposed to alter the tissue's biomechanical properties, thus predisposing to OA onset. The study presented here describes further investigation of two such age-related changes, cellular senescence and oxidative stress.

Source: OpenGrey (Institut de l'Information Scientifique et Technique)

Author: Scott, Jenny Louise

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6979782953

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Related to: 10