Evaluating Regioselectivity of Dienophile Adsorption to Tetracene via Diels-Alder Reaction in the Vapor Phase
Year: 2025
Type: conference-paper
Abstract: Diels-Alder synthetic reactions of organic compounds are fundamental to chemistry and have broad applications. Steep activation energy barriers control the regioselectivity of polycyclic aromatic hydrocarbon acenes, forming predictable adducts. However, initial data from our group suggests that strict regioselectivity may be altered when Diels-Alder reactions are performed in solid phase due to molecular packing. Our research examines how reaction cavity-specific effects in solid phase impact formation of unprecedented adducts, detected using mass spectrometry and Ultraviolet-Visible Spectroscopy techniques. The rules of Diels-Alder reactions in solid phase versus solution, and their application to alternative dienophiles with differing molecular properties, will be discussed.
Author: Rankin, Sophia Marie
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W6981666803
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