Year: 2023
Type: dissertation
Abstract: The endosomal trafficking system receives increasing attention as metabolic regulator. Particularly the liver requires proper trafficking function for metabolic control. Here, three different components of the endosomal trafficking system are examined for their function in liver metabolism. Importantly, depletion of these factors results in drastic metabolic changes, highlighting the importance of endosomal trafficking complexes for whole-body physiology with implications for metabolic disease.
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W6990926040
