Year: 2023
Type: dissertation
Abstract: Transmembrane proteins perform many essential tasks, including transport, signaling, regulation, and cell adhesion. Although they are very important and serve as targets for most drugs, only a minor fraction of known 3D protein structures represents transmembrane proteins. This dissertation presents a comprehensive overview over the membrane protein universe and the gradual evolution of methods designed to predict transmembrane proteins and their structural features.
Authors: Bernhofer, Michael, Rost, Burkhard, Technische Universität München
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: Alexander von Humboldt-Stiftung, National Research Foundation, Deutsche Forschungsgemeinschaft, Bundesministerium für Bildung und Forschung, Seoul National University, National Research Foundation of Korea, Israel Science Foundation, National Institutes of Health, National Institute of General Medical Sciences
OpenAlex ID: W6991053164