A multicenter,randomized controlled trial of individualized occupational therapy for patients with schizophrenia in Japan（統合失調症患者に対する個別作業療法：多施設共同ランダム化比較試験）
Year: 2018
Type: dissertation
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: The individualized occupational therapy (IOT) program is a psychosocial program that we developed to facilitate proactive participation in treatment and improve cognitive functioning and other outcomes for inpatients with acute schizophrenia.The program consists of motivational interviewing, self-monitoring, individualized visits, handicraft activities, individualized psychoeducation, and discharge planning.This multicenter, open-labeled, blindedendpoint, randomized controlled trial evaluated the impact of adding IOT to a group OT (GOT) program as usual for outcomes in recently hospitalized patients with schizophrenia in Japanese psychiatric hospitals setting compared with GOT alone.Patients with schizophrenia were randomly assigned to the GOT+IOT group or the GOT alone group.Among 136 randomized patients, 129 were included in the intent-to-treat population: 66 in the GOT+IOT and 63 in the GOT alone groups.Outcomes were administered at baseline and discharge or 3 months following hospitalization including the Brief Assessment of Cognition in Schizophrenia Japanese version (BACS-J), the Schizophrenia Cognition Rating Scale Japanese version, the Social Functioning Scale Japanese version, the Global Assessment of Functioning scale, the Intrinsic Motivation Inventory Japanese version (IMI-J), the Morisky Medication Adherence Scale-8 (MMAS-8), the Positive and Negative Syndrome Scale (PANSS), and the Japanese version of Client Satisfaction Questionnaire-8 (CSQ-8J).Results of linear mixed effects models indicated that the IOT+GOT showed significant improvements in verbal memory (p 0.01), working memory (p = 0.02), verbal fluency (p 0.01), attention (p 0.01), and composite score (p 0.01) on the BACS-J; interest/enjoyment (p 0.01), value/ usefulness (p 0.01), perceived choice (p 0.01), and IMI-J total (p 0.01) on the IMI-J; MMAS-8 score (p 0.01) compared with the GOT alone.Patients in the GOT+IOT demonstrated significant improvements on the CSQ-8J compared with the GOT alone (p 0.01).
Author: 島田, 岳
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6992941502