Takayasu’s arteritis with involvement of small cutaneous vessels - with regard to a clinical case
Year: 2025
Type: report
Abstract: Takayasu’s arteritis (AT) is a vasculitis that affects large vessels. Rarely, microcirculation is involved, sometimes with cutaneous manifestations. Inflammation of small vessels of the skin can present as erythema nodosum-like lesions, granulomatous cutaneous vasculitis, among others. We describe the case of a 29-year-old woman with a diagnosis of AT confirmed by Angio-CT. She was referred to a Dermatology appointment due to a skin condition characterized by centimetric, erythematous, painful and non ulcerated nodules on the soles and inner edges of the feet. Clinical and analytical criteria of active disease were met, despite implemented corticotherapy. Cutaneous biopsy showed panniculitis and leukocytoclastic vasculitis. Autoimmune vasculitis and cryoglobulinemia panels were negative. Erythema nodosum-like subcutaneous nodules have been described in TA, possibly preceding other disease manifestations or as markers of disease activity. An early correlation with constitutional and cardiovascular symptoms may lead to earlier diagnosis and prompt control of disease activity.
Authors: Ma. Cristina Fialho, Sara Castro, Sara Dias, Ricardo Veiga, Ana Ferreirinha, Emanuel Marques, Cândida Fernandes
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W6996933043
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