Work

Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to increase bedaquiline activity.

Year: 2024

Type: article

Abstract: Peer reviewed: True

Source: Apollo (University of Cambridge)

Authors: Fountain, Adam J, Waller, Natalie JE, Cheung, Chen-Yi, Jowsey, William, Chrisp, Michael T, Troll, Mark, Edelstein, Paul H, Cook, Gregory M, McNeil, Matthew B, Ramakrishnan, Lalita

Institution: Rockefeller University

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: University of Otago, Wellcome Trust, Royal Society Te Apārangi, Maurice Wilkins Centre for Molecular Biodiscovery, National Institutes of Health, Health Research Council of New Zealand, Marsden Fund, National Institute of Allergy and Infectious Diseases

Awards: G1376376908, Innate immunity and inflammation in tuberculosis: insights from the zebrafish and therapeutic opportunities, G7885692179, G962555551

OpenAlex ID: W6997445030

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