Influence of melatonin on the parametrs of the blood pro- and antioxidant condition of old rats under varying duraton of the photoperiod and immobilization stress
Year: 2023
Type: article
Abstract: An activation of lipid peroxidation and oxidative protein modification against a background of inhibited antioxidant defence (a decrease of the catalase activity and the content of the HS-group) is observed in the blood of old rats (20-24 months), that underwent immobilization stress under conditions of an altered seven-day photoperiod (12.00L:12.00D;24.00L:00D; 24.00D:00L). A three day administration to animals of melatonin in a dose of 2,5mg/kg against a background of a changed photoperiod and immobilization stress brought about a normalization of the parameters of the pro- and antioxidant blood state.
Author: Ломакіна, Ю.В.
Language: English
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7000973513
