Work

Antioxidant and Pro-Oxidant Effects of Polyphenolic Compounds and Structure-Activity Relationship Evidence

Year: 2012

Type: article

Abstract: The research and characterization of new bioactive substances, for the new design of functional foods, nutraceuticals, or drugs, has been intensified. Several studies showing controversial results of exogenous antioxidants, debating that the type, dosage and matrix of these antioxidants may be determining factors impacting the balance between beneficial and deleterious effects of these natural compounds (Bouayed & Bohn, 2010). There are also some proofs that they act as pro-oxidants, under certain conditions, such as high doses or the presence of metal ions (Decker, 1997; Raza & John, 2005; Watjen et al., 2005). The antioxidant or pro-oxidant activity intimately depends on their concentration (Bouayed & Bohn, 2010). The consequences of pro-oxidant activity could be the possible damage to the biomolecules such as DNA, proteins and lipids, and the consequent cellular death (Aruoma, 2003).

Source: Contact-less Assessment of In-vivo Body Signals Using Microwave Doppler Radar (InTech)

DOI: 10.60692/rmqwn-94t86

Authors: Estela Guardado, Enrique Molina, Mi Hyun Joo, Eugenio Uriarte

Institutions: University of Camagüey, Universidade de Santiago de Compostela

Language: English

Topic: Phytochemicals and Antioxidant Activities

Subfield: Biochemistry (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W6920664828

FWCI: 1.224

Cites:

Cited by: 72

Related to: 10