Work

Antimicrobial resistance in commensalEscherichia coliin veal calves is associated with antimicrobial drug use

Year: 2013

Type: article

Abstract: The aim of this study was to determine the association between farm management factors, including antimicrobial drug usage, and resistance in commensal Escherichia coli isolates from the faeces of white veal calves. Ninety E. coli isolates from one pooled sample per farm (n = 48) were tested for their phenotypical resistance against amoxicillin, tetracycline, cefotaxime, ciprofloxacin and trimethoprim/sulfamethoxazole (TMP/SMX). Logistic regression analysis revealed the following risk factors (P < 0·05); farmer wearing the same work clothes for several days [ciprofloxacin, odds ratio (OR) 2·6; tetracycline, OR 2·4], administration of trimethoprim-sulfonamide combinations (TMP/SMX, OR 3·0; amoxicillin, OR 3·1; tetracycline, OR 2·6), ⩾0·3 animal daily dosage per production cycle (ADD/pc), quinolones (ciprofloxacin, OR 2·8), ⩾1·3 ADD/pc, penicillins (ciprofloxacin, OR 3·3; tetracycline, OR 3·4), 20-40 ADD/pc, tetracyclines (tetracycline, OR 3·2) and >40 ADD/pc, tetracyclines (tetracycline, OR 13·1; amoxicillin, OR 6·5). In this study antimicrobial resistance in commensal E. coli was mainly associated with antimicrobial drug use.

Source: Epidemiology and Infection

DOI: 10.1017/s0950268813002665

Authors: A. B. BOSMAN, J. A. WAGENAAR, J. A. STEGEMAN, J. C. M. VERNOOIJ, D. J. MEVIUS

Institutions: Utrecht University, Wageningen University & Research

Language: English

Topic: Antibiotic Use and Resistance

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: bronze

Funders: Ministerie van Landbouw, Natuur en Voedselkwaliteit, Wageningen University and Research