Work

Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis

Year: 2018

Type: article

Source: Cell stem cell

DOI: 10.1016/j.stem.2018.10.013

Authors: Zhigang Cai, Jonathan J. Kotzin, Baskar Ramdas, Sisi Chen, Sai Nelanuthala, Lakshmi Reddy Palam, Ruchi Pandey, Raghuveer Singh Mali, Yan Liu, Mark R. Kelley, George Sandusky, Morvarid Mohseni, Adam Williams, Jorge Henao-Mejia, Reuben Kapur

Institutions: Indiana University Indianapolis, Indiana University School of Medicine, Indiana University – Purdue University Indianapolis, University of Pennsylvania, The Jackson Laboratory for Genomic Medicine, UConn Health, Children's Hospital of Philadelphia

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Leukemia and Lymphoma Society, National Institutes of Health, National Heart, Lung, and Blood Institute, National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Novel Mechanisms of C-Kit Regulation in Mast Cells, Targeting Novel Pathways in JMML, Regulation of group 1 ILCs by a novel lncRNA, Regulation of short-lived myeloid cells by the novel long non-coding RNA Morrbid, Exploiting the Ref-1 node in pancreatic cancer: tailoring new pancreatic cancer therapy using multi-targeted combinations, Role of Shp2 in FLT3-ITD induced leukemogenesis, Hyperglycemia mediated myeloproliferative disease, Regulation of adipose tissue inflammation by the miR-181 family, Basic Sciences Studies on Gene Therapy of Blood Diseases, Role of p21 activated kinase in Leukemogenesis, Hematopoietic stem and progenitor cell regulation for enhanced clinical efficacy

OpenAlex ID: W2905501602

FWCI: 20.08

Cites: 67

Cited by: 402

Related to: 10