Year: 2023
Type: dissertation
Abstract: First, we compared different sleep recording and sleep deprivation (SD) methods and found out there was no significant difference between them. Then, we did whole brain mapping on SD and undisturbed mice and found out several amygdala regions were active after SD. Next, we examined the function of cortical astrocytes in sleep homeostasis and noticed they promoted sleep when the mice were undisturbed. Last, we validated a restless legs syndrome (RLS) mouse model and found out they slept significantly less at the end of active period which is similar to RLS human patients.
Authors: Leu, Chia-Luen, Winkelmann, Juliane 1967-, Technische Universität München
Institutions: Technical University of Munich, Carleton University
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7010560594